Technology : Biotechnology And Intellectual Property Rights (IPR)

Q 2 / 34

UPSC CSE Prelims 2025

With reference to monoclonal antibodies, often mentioned in news, consider the following statements :

  1. They are man-made proteins.
  2. They stimulate immunological function due to their ability to bind to specific antigens.
  3. They are used in treating viral infections like that of Nipah virus.
Which of the statements given above are correct?

EXPLANATION

Correct Option (D)

All three statements are correct.

Statement I: Monoclonal antibodies (mAbs) are proteins produced artificially in laboratories. They are engineered to mimic the function of natural antibodies and are derived from a single clone of B lymphocytes, ensuring high specificity and uniform structure.

Statement II: Monoclonal antibodies stimulate immunological function by specifically binding to target antigens. These antigens can be found on the surface of pathogens, cancer cells, or other harmful molecules. This binding can neutralize the target, mark it for destruction by other immune cells, or block its activity, thereby triggering appropriate immune responses.

Statement III: Monoclonal antibodies have diverse therapeutic applications, including the treatment of various viral infections. Examples include their use against Nipah virus, Ebola virus, and SARS-CoV-2 (COVID-19). In the context of Nipah outbreaks, specific monoclonal antibodies have been administered under compassionate use protocols.

Incorrect Options

Options 1, 2, and 3 are incorrect because they omit one or more statements that are factually accurate regarding monoclonal antibodies and their applications.

SOURCEScience & Technology by Ravi Agrahari, Chapter: Biotechnology, The Hindu/Indian Express [Recent News on Nipah/Monoclonal Antibodies]